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Role of Adipsin in the Mechanism of Glucose Intolerance by Statin Therapy

A Prospective Study to Explore the Role of Adipsin in the Mechanism of Glucose Intolerance Developed as an Adverse Effect of Statin Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/11/010341
Enrollment
55
Registered
2017-11-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Newly diagnosed patients of dyslipidimia

Interventions

None listed

Sponsors

Dr Jahnavi Maini
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Treatment naive dyslipidemic patients (Low-density lipoprotein >=100mg/dl) or patients with ASCVD having dyslipidemia requiring statin therapy.

Exclusion criteria

Exclusion criteria: 1. Patient with comorbid Type 1 and Type 2 Diabetes Mellitus. 2. Patients prescribed lipid lowering agents other than statins. 3. Any known history of condition(s) which may cause secondary dyslipidemia (e.g. nephrotic syndrome, glycogen storage disease etc.). 4. Any history of condition(s) which may affect euglycemia (pancreatic impairment or disease). 5. History of previous or current muscular or neuromuscular disease. 6. History of drugs which impair lipid profile or glycemic parameters.

Design outcomes

Primary

MeasureTime frame
1. To estimate and compare the change in serum adipsin levels in dyslipidemic patients from baseline with that of serum adipsin levels after 12 weeks of statin therapyTimepoint: 12 weeks

Secondary

MeasureTime frame
2. To study the correlation of serum adipsin levels with serum insulin & HbA1c levels following 12 weeks of statin therapyTimepoint: 12 weeks;To estimation and comparison of serum levels of adipsin (mean ± SD) in statin treatment group and NHVTimepoint: baseline

Countries

India

Contacts

Public ContactDr Jahnavi Maini

Lady Hardinge Medical College

harmeetrehan@hotmail.com9811694040

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026