Comparison between skin based and hair based suspension in treatment of white hairs in vitiligo.

Comparison of efficacy of non-cultured extracted hair follicle outer root sheath cell suspension with non-cultured epidermal cell suspension in re-pigmentation of leukotrichia in vitiligo

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/11/010338

Enrollment

Registered

2017-11-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- VITILIGO

Interventions

Intervention1: Non cultured extracted hair follicle outer root sheath cell suspension transplantation: After hair follicle extraction by follicular unit extraction, cell suspension prepared by incubat

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients >= 15 years of age with vitiligo with at least one year duration of disease stability 2.Patients with minimum 1 vitiligo lesion with minimum of 15 leukotrichia hairs. 3.Patients consenting to participate in the study

Exclusion criteria

Exclusion criteria: 1.Pregnancy 2.Koebnerization 3.Keloid or bleeding diathesis 4.Active infection at the site 5.Inability to come for follow-up for at least 6 months 6.Patients with hair disorders

Design outcomes

Primary

Measure	Time frame
1.To compare the efficacy of NCEHFORSCS with NCES in the repigmentation of leukotrichia in vitiligo patch.Timepoint: at the end of 9 months post-surgical	—

Secondary

Measure	Time frame
1.To compare the efficacy of NCEHFORSCS with NCES in repigmentation of vitiligo. 2.Comparison of constituent cells like keratinocytes, melanocytes and melanoblasts in both the cell suspensions 3.We will attempt to find whether the melanocyte stem cells are lost in the bulge area of hair follicle in leukotrichia and if so, whether they are restored after the repigmentation of leukotrichia after transplantation in 5 patientsTimepoint: 9 months	—

Measure

Time frame

1.To compare the efficacy of NCEHFORSCS with NCES in repigmentation of vitiligo. 2.Comparison of constituent cells like keratinocytes, melanocytes and melanoblasts in both the cell suspensions 3.We will attempt to find whether the melanocyte stem cells are lost in the bulge area of hair follicle in leukotrichia and if so, whether they are restored after the repigmentation of leukotrichia after transplantation in 5 patientsTimepoint: 9 months

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Countries

India

Contacts

Public ContactDr Somesh Gupta

All India Institute of Medical Sciences

someshgupta@hotmail.com9868899120

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026