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Comparison of the adverse effects of common bronchodilators used in childhood wheezing

Comparison of the effects of salbutamol,levosalbutamol and ipratropium+salbutamol on heart rate .oxygen saturation,tremors and serum potassium levels..

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/11/010335
Enrollment
90
Registered
2017-11-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Children with wheezing

Interventions

Intervention1: Levosalbutamol: levosalbutamol 0.075 mg/kg/dose administered at intervals of twenty minutes for the first hour and then 6hrly for the next 24 hrs. Control Intervention1: salbutamol: sa

Sponsors

Bombay Hospital Trust
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children from one month to 18 years of age admitted to the pediatric ward with wheezing were included in the study.

Exclusion criteria

Exclusion criteria: Children admitted to the intensive care units, those with co-existing renal or cardiac abnormalities, known intolerance to the drugs or currently on medications known to lower serum potassium levels or cause tachycardia like oral beta 2 agonists and diuretics, were excluded from the study

Design outcomes

Primary

MeasureTime frame
Heart rate was measured by examination of the pulse and by a pulse oximeter. Oxygen saturation was monitored using a portable hand held pulse oximeter with a pediatric probe. Serum potassium levels were analysed by biochemical methods and tremors as reported by the parent or confirmed on clinical examination.Timepoint: All outcomes were measured at baseline.end of 1 hour and at the end of 24 hours

Secondary

MeasureTime frame
NILTimepoint: NA

Countries

India

Contacts

Public ContactSuba Sundaresan

Bombay Hospital Institute of Mdical sciences and research

doctormukesh@gmail.com9869134900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026