Health Condition 1: null- All the patients planned for elective laparoscopic cholecystectomy between 18-70yrs
Conditions
Interventions
Intervention1: dexamethasone: In one group of patients only one dose of 8mg dexamethasone by intra venous route will be given 90 minutes before surgery.
Control Intervention1: NIL
: NIL
Sponsors
Maharishi Markandeshwar Institute of Medical Science and Research
Eligibility
Inclusion criteria
Inclusion criteria: All the patients admitted and planned for elective laparoscopic cholecystectomy presenting in of Department of Surgery. Patients with both the sex fit for uncomplicated LC
Exclusion criteria
Exclusion criteria: Acute cholecystitis Pregnancy Patient having papillotomy by ERCP within one month Patients having preoperative nausea & vomiting Patients with hepatic and renal insufficiency History of corticosteroid hypersensitivity Patient receiving corticosteroids or immunosuppressive drugs Patients will be excluded if converted from Laparoscopic cholecystectomy to open procedure Any contraindiction of dexamethasone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of pre operative i.v dexamethasone 8mg on Post operative nausea and vomiting To evaluate the efficacy of pre operative i.v dexamethasone 8mg on analysis Pain and Fatigue on the basis of visual analogue scale and self reported registration To evaluate the efficacy of pre operative i.v dexamethasone 8mg on levels C-Reactive proteinTimepoint: at 0-1 hr at 1-2 hr at 2-3 hr at 3-6 hr at 6-24 hr at 24-48 hr at 3rd day | — |
Secondary
| Measure | Time frame |
|---|---|
| comperative evaluation of dexamethasone group with placeboTimepoint: at 0-1 hr at 1-2 hr at 2-3 hr at 3-6 hr at 6-24 hr at 24-48 hr at 3rd day | — |
Countries
India
Contacts
Public ContactDr Anand
Maharishi Markandeshwar Institute of Medical Science and Research
Outcome results
None listed