None listed
Conditions
Interventions
Intervention1: Almond and Diet Counseling: 43 g of cashew nut will be provided to the participants along with diet Counseling who will be randomized to intervention group for 3 months
Control Interven
Sponsors
Madras Diabetes Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: 1.BMI >=23 kg/m2 2.Central obesity 3.Dyslipidemia-low HDL and (or) high TGL
Exclusion criteria
Exclusion criteria: 1.Self reported diabetes 2.History of allergy to nuts 3.Use of nutritional supplements 4.Bad dentures 5.Weight loss diets 6.Pregnant/lactating women •Liver, kidney, thyroid, or other endocrine diseases •Any condition that hinders compliance to the intervention. •Possible eating disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the effects of almond supplementation on insulin resistance (HOMA IR) and beta cell dysfunction assessed by oral disposition index (DIo), C-peptide estimation and adiposity.Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the effect on the biomarkers of glucose metabolism (i.e., fasting glucose, and hemoglobin A1c), lipid profile (i.e., triglycerides, total cholesterol, LDL-cholesterol, and HDL-cholesterol), plasma fatty acid profile, satiety related gut hormones using multiplex panel (GLP-1, GIP, PYY and ghrelin) adiponectin and selected inflammatory markers (i.e., hs-CRP, TNF-α, MCP-1).Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactMrs Sudha Vasudevan
Madras Diabetes Research Foundation
Outcome results
None listed