Health Condition 1: null- Polycystic Ovarian Syndrome (PCOS)
Conditions
Interventions
Intervention1: Tab Dexamethasone 2 mg: Tab Dexamethasone 2 mg for 13-15 days, in addition to Tab Clomiphene Citrate 100 mg for 5 days.
Intervention2: Tab Dexamethasone 1 mg: Tab Dexamethasone 1 mg for
Sponsors
Research Fund Bangalore Baptist Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria (all criteria must be met): 1. Patients will be diagnosed as having PCOS according to the Rotterdam criteria for diagnosis of PCOS.26 2. All patients would have previously received CC 100 mg daily for 5 days per cycle and would have shown no response to this dose. 3. Semen analysis for their partners would have been evaluated according to the modified criteria of World Health Organization (2010) and found normal. 4. Age between 18 and 39 years. 5. Period of infertility >1 year.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Patients with hyperprolactinaemia, hypercortisolism, diabetes mellitus and thyroid dysfunction. 2. Patients receiving medications such as cholesterol-lowering drugs, beta-blockers and tricyclic antidepressants will also be excluded. 3. History of pelvic surgery or infertility factor other than anovulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The primary outcome would be the ovulation rate in the treatment cycle.Timepoint: 1. The primary outcome would be assessed from 13-17 day of the cycle. | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. The secondary outcomes would be: i. Number of follicles of 18 mm. ii. Endometrial thickness- checked on the day of follicular development. iii. Clinical pregnancy rate. Timepoint: i. 13-15 days ii. 13-15 days iii. 6 weeks | — |
Countries
India
Contacts
Public ContactDr Abha Khurana
Bangalore Baptist Hospital
Outcome results
None listed