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A simple bedside procedure for prevention of dye induced kidney failure in patients who are undergoing coronary angioplasty

Remote Ischemic Preconditioning for prevention of Contrast medium induced Nephropathy in patients at high risk of Contrast induced Nephropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010210
Enrollment
100
Registered
2017-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with coronary heart disease undergoing elective coronary angioplasty who are at high risk of Contrast induced Nephropathy

Interventions

Intervention1: REMOTE ISCHAEMIC PRECONDITIONING: REMOTE ISCHAEMIC PRECONDITIONING was accomplished by performing 4cycles of alternating 5-minute inflation and 5-minute deflation of a standard upper-

Sponsors

Government Medical college Thiruvanathapuram
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age >18 yrs 2. High risk of CIN : eGFR 30-60 ml/min/m2 3. Patients undergoing : CAG + adhoc PCI / Elective PCI. 4. Informed Writen Consent.

Exclusion criteria

Exclusion criteria: 1. Patient undergoing Routine Hemodialysis or Peritoneal Dialysis 2. Inability to perform RIPC due to pathology of both arms (for example, dystrophy, recent trauma, chronic wounds) 3. Patient on T. Gilbenclamide or T. Nicorandil

Design outcomes

Primary

MeasureTime frame
The primary outcome is the incidence of contrast induced nephropathy which is defined as an increment of serum creatinine by 0.5 mg/dL or a relative increase of 25% over the baseline value within a period of 48 hours after contrast medium administration.Timepoint: The follow up time points are 24 hours , 48 hours , 2 weeks and 6 weeks .—

Secondary

MeasureTime frame
Secondary outcomes include the maximum improvement of eGFR, maximum elevation in serum creatinine, occurrence of death, rehospitalization for heart failure and requirement of hemodialysis during a 6 week follow up period.Timepoint: The follow up time points are 24 hours, 48 hours, 2 weeks and 6 weeks.—

Countries

India

Contacts

Public ContactSanjai PV

Government Medical College, Thiruvananthapuram

spprasadam@gmail.com8289851669

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026