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A clinical trial to study the onset of action and duration of pain relief for two local anaesthetic drugs,bupivacaine and lignocaine which are used in nerve blocks for patients undergoing upper limb surgeries.

Double blinded randomised study of two different local anaesthetic solutions for ultrasound guided supraclavicular brachial plexus block.Bupivacaine alone or equal mixture of bupivacaine and lignocaine.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010183
Enrollment
50
Registered
2017-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA 1 and ASA2

Interventions

Intervention1: Ultrasound guided Supraclavicular brachial plexus block by using bupivacaine alone or equal mixture of lignocaine and bupivacaine: To compare the two different drugs onset and duration

Sponsors

Mahatma Gandhi Medical College and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA 1 and 2, undergoing elective or emergency procedure for upper limb surgeries at or below the elbow.

Exclusion criteria

Exclusion criteria: 1.Patient refusal for the block 2.History of bleeding disorders 3.Local infection at the site of block 4.Pre existing neurological deficit 5.Respiratory compromise 6.Known allergy to local anaesthetic drug 7.Patients in whom the supraclavicular sono anatomy is not clear

Design outcomes

Primary

MeasureTime frame
1)Time taken for Complete sensory block in al 4 nerves Median,Radial,Ulnar & Musculotaneous NerveTimepoint: Perception of sensation to ether soaked cotton was graded on a 3 point qualitative scale and will be assessed in every 5 min interval. 2 - Perceives both touch and temperature, 1 - Perceives only the touch but not the temperature, 0 - Perceives neither touch nor temperature. Score of 0 in all the four nerve distribution areas was taken as time to complete sensory block.

Secondary

MeasureTime frame
Complete motor block in all 4 nerves Median,radial,Ulnar&Musculocutaneous nerve and Duration of analgesiaTimepoint: Motor blockade will be graded for the four terminal brancheson a 3 point qualitative scale. 2 - Normal motor function (Power 4/5, 5/5) 1 - Decreased motor function (Power 3/5, 2/5) 0 - No motor function (Power 0/5, 1/5) Score of 0 in all the four nerve distribution areas was taken as time to complete motor block.

Countries

India

Contacts

Public ContactDaniel Rajadurai

Mahatma Gandhi Medical College and Research institute

docsripriya@gmail.com9365815939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026