To find out whether instillation of seminal fluid or drug (hCG) into the uterus will result in increased pregnancy rates

Efficacy of Intrauterine administration of seminal fluid or Human Choronic Gonadotrophin immediately after transvaginal oocyte retrieval on Implantation and pregnancy rate in IVF/ICSI treatment cycles - A randomised double blind trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/10/010182

Enrollment

Registered

2017-10-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Infertility patients

Interventions

Intervention1: hCG: IVF patients Control Intervention1: seminal fluid: IVF patients

Eligibility

Inclusion criteria

Inclusion criteria: The patients undergoing IVF/ICSI treatment at Bangalore Baptist Hospital, Department of Reproductive Medicine Unit as in patients. Inclusion Criteria: 1. Couples undergoing IVF/ICSI cycles with antagonist protocol. 2. Couples undergoing IVF/ICSI cycles with use of partnerâ??s (husband) fresh semen. 3. Couples undergoing IVF/ICSI cycles with female age Ë?38 years. 4. Couples undergoing IVF/ICSI cycles with various semen parameters. 5. Couples undergoing Day 3 Embryo Transfer.

Exclusion criteria

Exclusion criteria: 1. Couples undergoing IVF/ICSI cycles with female age Ë? 38 years. 2. Couples undergoing IVF/ICSI cycles with agonist protocol. 3. Couples undergoing Frozen embryo transfer. 4. Frozen semen samples. 5. Husband undergoing PESA/TESA (Percutaneous Epididymal Sperm Aspiration/Testicular Sperm Aspiration) 6. Poor Ovarian Reserve. AMH(Anti Mullerian Hormone) 7. Couples undergoing Day 5 Embryo Transfer.

Design outcomes

Primary

Measure	Time frame
percentage of implantation rateTimepoint: percentage of implantation rate. (within 6 weeks of IVF pregnancy).	—

Secondary

Measure	Time frame
percentage of clinical and ongoing pregnancy rateTimepoint: percentage of clinical and ongoing pregnancy rate. (Clinical pregnancy within 18days of Transvaginal oocyte retrieval and ongoing pregnancy rate within 12 weeks of IVF pregnancy.	—

Countries

India

Contacts

Public ContactS Latha

Bangalore Baptist Hospital

lathu_26@yahoo.in9663263952

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026