estimation of leptin levels in chronic gum disease subjects

Role of Non Surgical Periodontal Therapy on Leptin levels and Total Antioxidant Capacity in Chronic Generalised Periodontitis Patients - A Clinical Trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/10/010171

Enrollment

Registered

2017-10-24

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non Randomised Controlled trial. test group-chronic periodontitis subjects: test group - serum and saliva samples will be taken for measurement of leptin and total antioxidant levels. i

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects who are willing to give informed consent. 2.Subjects in the age group of 25 Ã¢â?¬â?? 55 years. 3.Subjects who have at least 20 functional teeth 4.Subjects with Chronic Generalised Periodontitis. (Which is Ã¢â?°Â¥30% of the sites showing Ã¢â?°Â¥3-4mm of clinical attachment loss with radiographic evidence of bone loss. 5.Subjects with normal body mass index (BMI) (18.5-22.9 kg/meter square) according to the chart for the Asian population given by WHO

Exclusion criteria

Exclusion criteria: 1.Subjects who are having Systemic diseases or are under regular medications for any systemic diseases. 2.Subjects who are on Anti-inflammatory/Anti-microbial therapy/mouthwashes or any vitamin supplements in the past 3 months. 3.Subjects who have undergone Periodontal Therapy in the last 6 months. 4.Pregnant or Lactating women. 5.Subjects who give a history of previous or current Smoking. 6.Subjects with Special Dietary requirements

Design outcomes

Primary

Measure	Time frame
1. To evaluate levels of leptin and Total Antioxidant Capacity in patients with Chronic Periodontitis after Non Surgical TherapyTimepoint: baseline- subjects enrollment and saliva and serum sample collection. 1 month recall clinical parameter measurement 3 months recall reevaluation of saliva and serum samples . 6 months duration study	—

Secondary

Measure	Time frame
to correlate the leptin levels and total antioxidant capacity in chronic generalised periodontitis patientsTimepoint: 3 months and 6 months- subjects enrollment and saliva and serum sample collection.	—

Countries

India

Contacts

Public ContactDr Swet Nisha

JSS Dental College and Hospital

dravinashbs@gmail.com9945047223

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026