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Relationship between stress markers in smokers and nonsmokers with chronic periodontal disease

Association of Stress, Serum and Salivary Cortisol and Interleukin-1beta Levels in Chronic Periodontitis in Smokers and Non Smokers

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/10/010158
Enrollment
75
Registered
2017-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Smokers and non smokers with chronic periodontits

Interventions

Control Intervention1: stress levels and serum and salivary cortidol and interlukin 1 beta levels: Clinical periodontal parameters and stress levels and serum and salivary cortisoland interlukin 1 Bet

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Group I Periodontally healthy subjects with no signs of periodontal disease. Group II Current Smokers with untreated moderate to severe chronic periodontitis Group III Nonsmokers with untreated moderate to severe chronic periodontitis

Exclusion criteria

Exclusion criteria: 1.Patients with self reported psychiatric disorders or psychotic medications. 2.Patients with any systemic disease. 3.Pregnant and post menopausal women. 4.Patients with history of antibiotic intake within 6 weeks. 5.Patients undergoing corticosteroids or immunosuppresive therapy. 6.Patients with acute illness.

Design outcomes

Primary

MeasureTime frame
Evaluating levels of stress serum and salivary Cortisol and Interleukin 1 beta in smokers and nonsmokersTimepoint: by June 2017—

Secondary

MeasureTime frame
Evaluating association of stress serum and salivary Cortisol and Interleukin 1 β in smokers and nonsmokers compared to healthy controlsTimepoint: July 2017—

Countries

India

Contacts

Public ContactDrAbhay P Kolte

VSPM Dental College and Research Centre

drabhaypkolte@gmail.com9011071467

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026