Argon coagulation versus enema for chronic radiation proctitis

Efficacy of Argon plasma coagulation and steroid sucralfate retention enema in reducing bleeding in chronic radiation proctitis-a randomized controlled trial - APC versus SSE in CRP

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/10/010096

Enrollment

110

Registered

2017-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CHRONIC RADIATION PROCTITITS

Interventions

Intervention1: Argon plasma coagulation.: APC will be applied at an average power of 50 W by using an ERBE APC generator (TÃ¼bingen, Germany) with flow rate of 5L/min.The goal of treatment is to ablat

Eligibility

Inclusion criteria

Inclusion criteria: Patients with symptoms of bleeding per rectum 90 days following radiotherapy for carcinoma cervix

Exclusion criteria

Exclusion criteria: Residual malignancy Fistula Stricture/stenosis Rectal mucosal ulcers Patients who received any surgical treatment for radiation proctitis Bleeding diathesis.

Design outcomes

Primary

Measure	Time frame
recurrence of bleeding per rectumTimepoint: 6 months after completion of treatment	—

Secondary

Measure	Time frame
Sigmoidoscopic grade as assessed by the Vienna sigmoidoscopic gradeTimepoint: 6 months after completion of treatment	—

Countries

India

Contacts

Public ContactShyama Prem Sudha

JIPMER, Puducherry

shyamagopalakrishnan@yahoo.co.in9787814215

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026