Health Condition 1: null- ASA Status 1 & 2.
Conditions
Interventions
Intervention1: intravenous drug administration: Study drug(magnesium sulphate) and placebo(normal saline) will be given intravenously 10 minutes prior to induction of anaesthesia. Dose of magnesium su
Sponsors
Indira gandhi Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective abdominal surgery under general anaesthesia. 2.Aged between 20-60 years. 3.ASA grade I & II. 4.Those who are willing to give written consent.
Exclusion criteria
Exclusion criteria: 1.Persons with pre existing neurological or spinal disease. 2.cardiovascular, respiratory, renal, hepatic or any other systemic disease 3.Allergic to magnesium sulphate. 4.Extreme of ages ï?? Patients not willing to take part in study. ï?? Expected Duration of surgery more than 2 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain score using Numeric Rating Scale and total analgesic consumption post operatively.Timepoint: Pain score at emergence of anesthesia and at 6, 12, 18 and 24â??h after the surgery.dosage of post operative analgesia will be recorded at 0, 6, 12, 18 and 24 after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in vital parameters ( heart rate, blood pressure, oxygen saturation) and symptoms of hypermagnesemia or any adverse effects if any.Timepoint: vital parameters will be assessed every 5 minutes intra-operatively and every 15 minutes post-operatively. other adverse effects will be recorded if occurs any time intra operatively and post operatively till 24 hours. | — |
Countries
India
Contacts
Public ContactDr Chandrakant Prasad
Indira Gandhi Institute of Medical Sciences
Outcome results
None listed