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A study to compare efficacy of bupivacaine (density more than csf)and levobupivacaine (density equal to csf) when given in subarachnoid space in cases of urological surgeries.

A comparative study of intrathecal hyperbaric bupivacaine and isobaric levobupivacaine in urological surgeries.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010087
Enrollment
100
Registered
2017-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA Status 1 & 2

Interventions

Intervention1: Subarachnoid block: Subarachnoid block will be given in L3-L4 subarachnoid space using 26G whitacre spinal needle after confirming free flow of CSF. Control Intervention1: Hyperbaric Bu

Sponsors

Indira Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients undergoing elective urological surgery under spinal anaesthesia. 2)Aged between 30-60 years. 3)ASA grade 1 & 2. 4)Those who are willing to give written consent.

Exclusion criteria

Exclusion criteria: 1) persons with pre existing renal, cardiovascular,hepatic or other systemic diseases. 2)bleeding diathesis. 3)infection at the site of block 4)abnormalities of spine 5)Aspirin ingestion in preceeding week

Design outcomes

Primary

MeasureTime frame
Onset, Duration, and level of motor and sensory block, motor and sensory regression period.Timepoint: time to reach t-9 sensory level will be taken as onset time.time to 1st rescue analgesic after surgery will give duration of analgesia. level of block will be assessed every 5 minutes till 30 minutes after block. motor and sensory regression will be assessed every 15 minutes post-operatively.

Secondary

MeasureTime frame
any adverse effect like nausea, vomiting, hypotension, bradycardia or breathing difficulty.Timepoint: hypotension, bradycardia will be assessed every 5 minutes intra-operatively and every 15 minutes post-operatively. other adverse effects will be recorded if occurs any time intra operatively and post operatively till the regression of sensory block.

Countries

India

Contacts

Public ContactDr Chandrakant Prasad

Indira Gandhi Institute of Medical Sciences

drvvinodv@gmail.com9473191825

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026