FindTrial
Sign In

Benefit of giving estrogen in IVF cycles.

To determine the efficacy of estradiol along with progesterone as luteal phase support support in women undergoing In -Vitro fertilization.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010083
Enrollment
150
Registered
2017-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Infertile patients undergoing IVF

Interventions

Intervention1: Study group: Luteal phase supplementation in form of Estradiol Valerate 2mg tablet twice a day orally along with injectable micronized progesterone and vaginal micronized progesterone.

Sponsors

Maulana Azad Medical College and Lok Nayak Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women receiving long protocol of down regulation with GnRH agonist and controlled ovarian stimulation with gonadotropins.

Exclusion criteria

Exclusion criteria: Serum E2 >3000pg/ml on day of oocyte retrieval, Diminished ovarian reserve( Day2 serum FSH >10mIU/ml), Endometriosis greater than stage2, Severe male factor(less than 5million/ml motile spermatozoa), Endocrine disorders, Medical or surgical illness.

Design outcomes

Primary

MeasureTime frame
Pregnancy rate in two groupsTimepoint: After 14days of Embryo transfer.—

Secondary

MeasureTime frame
Serum levels of Ethinyl Estradiol and Progesterone.Timepoint: On the day of oocyte retrieval, day of embryo transfer, three days after embryo transfer and on day day of results, ie, 14days after embryo transfer.—

Countries

India

Contacts

Public ContactAishwarya Kapur

Department of Obstetrics and Gynaecology, Maulana Azad Medical College,Delhi

drsprasad@yahoo.com9968604341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026