None listed
Conditions
Interventions
Intervention1: Intrauterine insemination(IUI) with endometrial scratching: Endometrial scratching will be done on day 8 or day 9 of the menstrual cycle planned for IUI using endometrial pipelle biospy
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: Couples attending the Infertility outpatient clinic in OBG Dept with up to three previous failed IUI. 1. Couples with mild male factor infertility- defined According to WHO (2010) as sperm analysis : A.Sperm Concentration >10-20x106 sperm/ml B.15-25% progressive motility and / or C. 2. Couples with unexplained infertility â?? A. Regular normal Menstrual cycles B. Bilateral fallopian tubes patent-confirmed by laparoscopy or hysterosalphingography C. Normal TSH and Prolactin levels D. Normal reproductive hormone levels E. Normal semen analysis
Exclusion criteria
Exclusion criteria: 1. Endometriosis or intrauterine organic pathology (polps,myoma and adhesions) , known Pelvic inflammatory disorder, ovarian cyst. 2. Any other medical disorder (Cardiovascular, Renal and Hepatic Disorders).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Higher pregnancy rates with endometrial scratching in patients undergoing IUI .Timepoint: Assessed in months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the number of attempts at endometrial scratching in subsequent cycles to attain pregnancyTimepoint: Assessed in Months;To assess the pain and bleeding following endometrial scratching.Timepoint: Pain will be assessed based on Visual analog scale, right after procedure and bleeding graded as minimal/mild/moderate following procedure. | — |
Countries
India
Contacts
Public ContactDrChitra T
JIPMER
Outcome results
None listed