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A clinical trial to study the effects of two drugs, Tranexamic acid and Hydroquinone in patients with melasma

A COMPARATIVE STUDY ON THE EFFICACY OF TOPICAL 5% TRANEXAMIC ACID SOLUTION VS 3% HYDROQUINONE CREAM IN MELASMA.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010049
Enrollment
100
Registered
2017-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Melasma

Interventions

Intervention1: 5% Tranexamic acid solution: 50 patients of melasma are asked to apply 5% Tranexamic acid solution at night for 12 weeks Control Intervention1: 3% Hydroquinone cream: 50 patients are as

Sponsors

Dr Manasa S J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Previously treated cases of melasma,not applying topical medication for past 1 month.

Exclusion criteria

Exclusion criteria: 1. Pregnant and nursing women. 2.Women on OCPs 3.Patients on photosensitizing drug.4.Patients with clotting disorders 5. Patients on concurrent treatment for melasma.

Design outcomes

Primary

MeasureTime frame
Reduction in mean MASI score Timepoint: 0,4,8,12th week—

Secondary

MeasureTime frame
No improvement in MASI scoreTimepoint: 12 weeks—

Countries

India

Contacts

Public ContactDr Manasa S J

Command Hospital Airforce

drsrkskin@gmail.com9449275068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026