Health Condition 1: null- ASA I & II patients, between age group18-60yrs with BMI (30-40kg/m2), undergoing elective laparoscopic surgery under general anaesthesia for atleast 30 minutes and maximum of 3 hours
Conditions
Interventions
Intervention1: Intravenous propofol: The dose of intravenous propofol calculated as per the Lean Body weight as a bolus at induction and infusion for maintenance of general anaesthesia throughout the
Sponsors
Dr L H Hiranandani Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective laparoscopic surgery with BMI between 30 and 40, ASA 1and 2 under general anaesthesia for a minimum duration of 30 minutes to maximum of 3 hours
Exclusion criteria
Exclusion criteria: 1.History of significant cardiac pulmonary, liver or renal disease. 2. Patient scheduled for awake bronchoscopic intubation. 3. Previous history of cerebrovascular accident, other neurological disorders and those on long term drugs affecting CNS (chronic BZDâ??s/ opioids) 4. Allergy to propofol. 5. Patients with significant hemodynamic changes intraoperatively, fall of Mean arterial blood pressure by more than 20% of baseline,intraoperative entropy of more than 60 for more than 10 minutes and need to add inhalational agent will be excluded. 6) patients refusal to be included in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ideal weight scalar for assessing the dose of propofol for induction and maintanence of total intravenous general anaesthesia in laprascopic surgeryTimepoint: Industion dose- after one minute of injection of the bolus dose of intravenous propofol at induction of anaesthesia maintenance dose- the average infusion dose for maintenance of anaesthesia with intravenous propofol throughout the duration of surgery, calculated at the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery parameters like 1 Sedation score post extubation 2 Time for extubation after stoping propofol infusion 3. Time for eye opening after stopping propofol infusion 4. Time for obeying oral commands after stopping propofol infusion 5. Time to achieve entropy values more than 90 after stopping propofol infusionTimepoint: After stopping propofol infusion 1. Sedation score - post extubation 2. Time for extubation - time required after stopping propofol infusion to the time of extubation 3. Time for eye opening after stopping propofol infusion to the time of extubation 4. Time for obeying oral commands after stopping propofol infusion to the time of extubation 5. Time taken to achieve entropy values more than 90 after stopping propofol infusion | — |
Countries
India
Contacts
Public ContactDr Manisha Gaikwad
Dr L H Hiranandani Hospital
Outcome results
None listed