Health Condition 1: null- Uncontrolled diabetes mellitus
Conditions
Interventions
Intervention1: Vitamin C: Evaluation of Effect of Vitamin C Adjuant Therapy in Patients with Diabetes Mellitus
Control Intervention1: Atorvastatin: Effect of Vitamin C Adjuant Therapy on Lipid Profile
Sponsors
School of pharmaceutical sciences
Eligibility
Inclusion criteria
Inclusion criteria: patients diagnosed with type 2 diabetes mellitus for a period of not less than 2 years with co-morbid cardiovascular disease (new onset/past history), whose blood sugar profile is uncontrolled as indicated by HbA1c above 8.0, in treatment with the standard treatment regimen for diabetes mellitus as per the recommended guidelines and willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with concomitant life threatening illness, including myocardial infarction, ischemic stroke or risk of developing NSTEMI, STEMI. 2. Patients with metabolic acidosis 3. Patients who had a history of renal calculi
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of effet of Vitamin C Adjuant therapy significance on lipid profile and HbA1c in diabetes patients with co-morbid cardiovascular disease.Timepoint: Baseline, 1st month, 2nd month and 3rd month. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adjustment for factors those confounds the effect of vitamin therapy on lipid profile and thereby quantify the extent of the effectTimepoint: Baseline, 1st month, 2nd month and 3rd month.;Assessement of the acute effect of Vitamin C adjuant therapy on serum C-reactive protein.Timepoint: Baseline, 1st month, 2nd month and 3rd month.;Evaluation of Incidence of elevated CRP levels in diabetic patients with dislipidemiaTimepoint: Baseline, 1st month, 2nd month and 3rd month. | — |
Countries
India
Contacts
Public ContactSubalakshmi
Vels university
Outcome results
None listed