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Comparison of graft patency in on-pump heart surgery versus off-pump heart Surgery

Prospective Randomized comparison of Off-pump and On-pump Multi-vessel Coronary artery bypass surgery To Evaluate outcomes and graft patency

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/10/010030
Enrollment
400
Registered
2017-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Multi-vessel Coronary Artery Disease Health Condition 2: I220- Subsequent ST elevation (STEMI) myocardial infarction of anterior wall

Interventions

Intervention1: Off-Pump CABG: Beating Heart Surgery Control Intervention1: On-Pump CABG: Heart Surgery on Cardiopulmonary Bypass

Sponsors

Dr Lokeswara Rao Sajja
Lead Sponsor
Dr Gopichand Mannam
Collaborator
Dr Kunal Sarkar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male or female aged >=21years to 2. Able to provide written informed consent 3. Patients with significant CAD with significant triple vessel disease or LMCA stenosis angiographically documented ischemia due to multi vessel coronary artery disease 4. Require isolated CABG 5. LVEF >= 40 %

Exclusion criteria

Exclusion criteria: 1. CABG with concomitant valvular procedures 2. CABG with concomitant repair of congenital heart disease. 3. Contra-indications to off-pump CABG or on-pump CABG (calcified aorta, intramuscular LAD, calcified coronaries, small target vessels, resection of ventricular aneurysm) 4. Severe congestive heart failure, Ney York Heart Association (NYHA) Class III or IV or pulmonary edema. 5. Chronic atrial fibrillation 6. Allergy to contrast material 7. Prior valve replacement or Redo CABG 8. Prior percutaneous coronary intervention (PCI) with stent implantation within 3 months 9. Concomitant medical disorders making clinical follow-up at least 3months unlikely or impossible e.g. neoplastic, hepatic, or other severe disease 10. Emergency CABG 11. LVEF 12. Unable to give consent

Design outcomes

Primary

MeasureTime frame
The primary outcome is the assessment of Conventional coronary angiographic patency of the grafts at 3 months.Timepoint: The primary outcome is the assessment of Conventional coronary angiographic patency of the grafts at 3 months.—

Secondary

MeasureTime frame
The secondary outcome is the occurrence of the composite of cardiovascular death, stroke, nonfatal MI, or new onset renal failure (AKI) requiring CRRT.Timepoint: At 3 months—

Countries

India

Contacts

Public ContactDr Lokeswara Rao Sajja

STAR Hospitals

sajjalr@yahoo.com91-9849028317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026