Health Condition 1: null- Verruca plana
Conditions
Interventions
Intervention1: Isotretinoin: Capsule Isotretinoin in the dose of 0.5 mg/kg body weight administered for a period of 3 months
Control Intervention1: Placebo: Placebo capsules given for a period of 3 mo
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: The inclusion criteria were age more than 5 years, untreated or patients off treatment for 4 weeks before entering the study. It was ensured that females enrolled in the study were either using two forms of contraception (OCP/ IUD/ Barrier) or had permanent method of sterilisation (tubectomy or vasectomy in partner).
Exclusion criteria
Exclusion criteria: The exclusion criteria were pregnancy and lactation; age less than 5 years; systemic disorders including liver dysfunction, hyperlipidemia, connective tissue disorders, photosensitive disorders and psychiatric illness; treatment with drugs like vitamin A, tetracyclines, steroids or on laser treatment; uncooperative patients and patients with unrealistic expectations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clearance of lesionsTimepoint: Complete: 100% response i.e. complete disappearance of warts Partial: more than 50% response. No response: less than 50% response | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of recurrence and drug safety profileTimepoint: During treatment period and follow up period, total duration of 6 months | — |
Countries
India
Contacts
Public ContactDr Vaishali Masatkar
Senior Professor, Department of Dermatology
Outcome results
None listed