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To study the efficacy of Clomiphene Citrate and Letrozole in ovulation induction

Comparison of the use of Clomiphene Citrate and Letrozole in women undergoing Intrauterine Insemination

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/10/010003
Enrollment
100
Registered
2017-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Women undergoing ovulation induction followed by intrauterine insemination

Interventions

None listed

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women below the age of 38 years and undergoing ovarian stimulation/induction and Intra uterine insemination(IUI) for Type II anovulatory infertility, unexplained infertility mild male factor infertility or heterologous insemination(HI)

Exclusion criteria

Exclusion criteria: Anovulatory cycles following stimulation, tubal factor, male factor where IUI is not an option, co existing pelvic pathology like Fibroids, Endometriosis, sequelae of PID

Design outcomes

Secondary

MeasureTime frame
Pregancy ratesTimepoint: Pregnancy rates will be assessed by the appearance of cardiac activity for the first time on scans done at 6 weeks after IUI.

Primary

MeasureTime frame
1) The number of leading follicles and size of follicles on the day of trigger 2) The day of the cycle on which the follicles where ready for trigger i.e. The size of follicles more than 18mm 3) Endometrial thickness and pattern on the day of trigger 4) Ovulation rate 5) The relation between the doses of clomiphene citrate used 50/100 mg and follicular and endometrial responseTimepoint: On the Day 11 of the menstrual cycle follicular imaging will be done and number and size of the follicles will be assessed. The follicular imaging will be done on alternate days till leading follicle is more than 18mm.

Countries

India

Contacts

Public ContactDr Sneha Subodh Kumar Singh

Kasturba Medical College, Manipal

astra117us@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026