Health Condition 1: J988- Other specified respiratory disorders Health Condition 2: null- Premature neonates at birth
Conditions
Interventions
Intervention1: 8-10 litres/min of nasal high flow therapy: 8-10 litres/min of heated humidified nasal high flow thearpy initiated in preterm infants with respiratory distress within 6 hrs of birth
Con
Sponsors
Surya Children Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Preterm infants more than 28 weeks of gestation and/or more than 1 kg birth weight with respiratory distress and FiO2 requirement >30% within first 6 hours of birth.
Exclusion criteria
Exclusion criteria: 1) Birth weight 2) Gestational age 3) Infant who already received surfactant 4) Pneumothorax on Chest X-ray 5) Shock requiring inotropic support, multi organ dysfunction and encephalopathy 6) Abnormalities of upper and lower airways precluding use of HHHFNC (Pierre-Robin, Treacher Collins, Goldenhar, choanal atresia, cleft lip/palate) 7) Serious abdominal, cardiac, or respiratory malformations including tracheal esophageal fistula, intestinal atresia, omphalocele, gastroschisis, or diaphragmatic hernia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HHHFNC failure rate -composite outcome defined by the need of a) CPAP support b) surfactant treatment c) mechanical ventilationTimepoint: from birth until fifth day of postnatal age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of respiratory support 2. Duration of oxygen therapy. 3. Need of CPAP 4. Need of surfactant treatment 5. Need of mechanical ventilation 6. Mortality due to any cause. 7. Pulmonary air leaks (pneumothorax, pulmonary interstitial emphysema) 8. Nasal injuriesTimepoint: from admission until NICU discharge | — |
Countries
India
Contacts
Public ContactDr Bhawandeep Garg
Surya Childrens Hospital
Outcome results
None listed