Health Condition 1: null- Pregnancy with PreEclampsia
Conditions
Interventions
Intervention1: Intravenous Labetalol: Combined alpha plus beta blocker for severe hypertension in pregnancy.
Patients randomized to intravenous labetalol received 20 mg initially followed by escalatin
Sponsors
Government Siddhartha Medical College
Eligibility
Inclusion criteria
Inclusion criteria: All antenatal women of gestational age >28 weeks with severe hypertension with systolic blood pressure (BP) of 160 mm Hg or higher and/or diastolic BP of 110 mm Hg or higher on 2 separate occasions 30 minutes apart in lateral recumbent position
Exclusion criteria
Exclusion criteria: 1. Patients with history of cardiac disease 2. Patients with history of bronchial asthma 3. Patients with history of haematological disorder 4. Patients with history of allergy to labetalol or nifedipine 5. Patients with liver disorders 6. Maternal heart rate 120 bpm 7. Patients with history of exposure to any anti-hypertensive medications in the past 24 hours 8. Patients with chronic hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time taken in minutes,by either drug to achieve the target blood pressure of systolic BP 150mmHg and/or diastolic BP 110mmHg.Timepoint: Mean time taken to achieve target blood pressures in a set study population for a period of two years | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of doses required Adverse effects Maternal and perinatal oucomeTimepoint: mean number of doses required, adverse effects and maternal and perinatal outcome in a set study population at the end of 2 years | — |
Countries
India
Contacts
Public ContactMomina Zulfeen
Govt. Siddhartha Medical College
Outcome results
None listed