Health Condition 1: null- All patients in the age group 18 to 65 years requiring flexible bronchoscopy in the Department of Respiratory Medicine.
Conditions
Interventions
Intervention1: MIDAZOLAM: Patients in Group A will recieve Normal Saline/Midazolam 0.035 mg/kg
Control Intervention1: DEXMEDETOMIDINE: Patients in group B will recieve Dexmedetomidine 0.5 µg/kg /Nor
Sponsors
Kasturba Medical College Manipal
Eligibility
Inclusion criteria
Inclusion criteria: All patients in the age group 18 to 65 years requiring flexible bronchoscopy in the Department of Respiratory Medicine.
Exclusion criteria
Exclusion criteria: 1.Patients with known or suspected allergy to Midazolam or Dexmedetomidine 2.Patients with renal or hepatic insufficiency 3.Patients with seizure disorder 4.COPD patients with FEV1 5.Patients with psychiatric disorder 6.Haemodynamically unstable patients including cardiac failure 7.Heart rate 8.Patients with body weight more than 70kg. 9.Pregnancy and lactation 10.Hypovolemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Composite score during the bronchoscopy procedure. 2.Numerical Rating Scale (NRS)for pain intensity and distress. 3.Visual Analogue Scale for cough. 4.Ease of bronchoscopy procedure. 5.Ramsay sedation score. 6.Post- procedure patient response after 24hours.Timepoint: Prior, during, 10mins after bronchoscopy and 24hours after bronchoscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Duration of bronchoscopy procedure. 2.Number of doses of rescue medication required during the procedure. 3.Haemodynamic variables such as Heart rate , systolic blood pressure, and diastolic blood pressure 4.Oxygen saturation . 5.Lignocaine dose used Timepoint: BASELINE,START OF FB,5 MINUTES AFTER THE START OF FB,10 MINUTES AFTER THE START OF FB,END OF FB,10 MINUTES AFTER THE END OF FB. | — |
Countries
India
Contacts
Public ContactDR RAHUL MAGAZINE
KASTURBA MEDICAL COLLEGE, MANIPAL
Outcome results
None listed