Health Condition 1: null- septic shock in neonates due to late onset sepsis
Conditions
Interventions
Intervention1: sodium as 3 mmol/kg/day: sodium as 3 mmol/kg/day in intravenous fluids in septic shock due to late onset sepsis
Control Intervention1: sodium as 2 mmol/kg/day: sodium intake as 2 mmol/k
Sponsors
jipmer hospital
Eligibility
Inclusion criteria
Inclusion criteria: Neonates with birth weight of more than 1500 grams with septic shock due to late onset sepsis (sepsis presentation after 72 hours of life). Only neonates born to adult parents will be included in study
Exclusion criteria
Exclusion criteria: Neonates with shock due to other etiology Birth weight less than 1500 grams Congenital heart disease Acute kidney injury at admission Hyponatremia at admission Major surgical conditions and lethal congenital anomalies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the incidence of hyponatremia in neonates with septic shock when administering sodium intravenously at the rate of 3mmol/kg/day vs 2 mmol/kg/day.Timepoint: the study will be terminated when shock resolves or hyponatremia develops | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the duration of septic shock in these neonates To assess the mortality among these neonates with septic shock Timepoint: the study will be terminated when shock resolves or hyponatremia develops | — |
Countries
India
Contacts
Public Contactdr chetan khare
jipmer hospital
Outcome results
None listed