Health Condition 1: null- Urinary Tract Infection Health Condition 2: N390- Urinary tract infection, site notspecified
Conditions
Interventions
Intervention1: Fosfomycin Tromethamine: One Sachet containing 3gms of fosfomycin trometamine in powder form to be taken as a single dose in a glass of water.
Control Intervention1: Ciprofloxacin: Tab
Sponsors
University College of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients aged above 18 years giving informed consent to participate in the study 2. Patients with clinical symptoms of uncomplicated UTI 3. Patients with pyuria documented on dipstick leucocyte esterase or by urine microscopy with pus cells.
Exclusion criteria
Exclusion criteria: 1. Patients not willing for consent for inclusion in the above study. 2. Asymptomatic bacteriuria 3. Complicated UTI 4. Patients on any antibiotic therapy in the last 48 hours 5. Patients with known drug allergy to Ciprofloxacin or Fosfomycin 6. Patients with known contraindications to Ciprofloxacin or Fosfomycin 7. Patients on Metoclopromide, pregnancy, children
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Subjective Clinical relief of symptoms. 2. Absence of pyuria by negative urine dipstick leucocyte esterase test . Timepoint: 3rd day | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bacterial spectrum, antimicrobial sensitivity pattern, of symptomatic UTI (with special reference to Fosfomycin). 2. Incidence of UTI caused by extended spectrum β-lactamase producing (ESBL) strains of Escherichia coli. 3. To evaluate the possible risk factors in the causation of UTI in our patient setting. 4. Side effects, ADRs and ADEs following administration of the drugs. Timepoint: 3rd day | — |
Countries
India
Contacts
Public ContactDr Sheikh Mohd Murtaza
University College of Medical Sciences University of Delhi GTB Hospital
Outcome results
None listed