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Examination of the pupil in eye to see the fall in Blood Pressure after injection of anesthetic drug in back of patient with diabetes

Dynamic Pupillometry to predict hypotension after spinal anaesthesia in patients with Diabetes Mellitus - An analytical study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/09/009903
Enrollment
75
Registered
2017-09-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adults with diabetes mellitus aged 20-60yrs, height-140-180cm, weight-45-75kg

Interventions

Intervention1: NIL: NIL

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adults with diabetes mellitus in the age-group of 20-60 years undergoing elective surgical procedures under spinal anaesthesia. 2. Height: 140cm-180cm 3. Weight: 45-75kg

Exclusion criteria

Exclusion criteria: 1. Patient refusal for spinal anaesthesia 2. Patients taking drugs affecting sympathetic and parasympathetic pupillary function 3. Patients with h/o ocular operations, anisocoria, misshapen pupil or conditions affecting pupillary reflexes 4. Patients with other comorbidities like Hypertension, Hyperthyroidsm, Hypothyroidism, Asthma, COPD , Heart diseases except Diabetes. 5. Patients in whom more than 1000ml of blood loss is anticipated. 6. Patients with coagulopathy 7. Pregnant patients

Design outcomes

Primary

MeasureTime frame
Changes in the pupillometric variables within a patient over time can indicate the autonomic dysfunction. This change can be assessed preoperatively. Thus the severity of the hypotension can be predicted and necessary precautions can be taken to overcome the complications.Timepoint: blood pressure will be measured in every 5 minutes after spinal anesthesia

Secondary

MeasureTime frame
To assess the vasopressor requirement intra-operatively.Timepoint: intra-operative if Blood pressure falls 20% below baseline

Countries

India

Contacts

Public ContactDrV Stalin

JIPMER

drvstalin@gmail.com9786397762

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026