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vitamin D and thyroid disease

Changes in auto antibody and cytokine levels following Vitamin D supplementation in subclinical autoimmune hypothyroidism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009889
Enrollment
50
Registered
2017-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- autoimmune subclinical hypothyroidism vitamin D deficiency

Interventions

Intervention1: vitamin D: this is a single arm trial parameters are assayed before and after vitamin D supplementation Intervention2: vitamin D: Single arm trial. vitamin D 60, 000 units per week ora

Sponsors

Rajiv Gandhi university of Health sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subclinical hypothyroidism (TSH 4.1-10 IU/l) 2. TPO-Ab positivity 3 Vitamin D deficiency (levels

Exclusion criteria

Exclusion criteria: 1. Previous therapy with thyroxine 2. pregnancy 3. hypercalcemia

Design outcomes

Primary

MeasureTime frame
change in cytokine (IL6,TNF alpha, IL2, IFN gamma, IL4, IL 17) levelsTimepoint: 0 month and 6 months—

Secondary

MeasureTime frame
anti-thyroid peroxidase and anti-thyroglobulin antibody levelsTimepoint: 0 month 6 months;TSH levelsTimepoint: 0 month 6 months—

Countries

India

Contacts

Public ContactJyothi Idiculla

St Johns Medical College

jyothi_idiculla@yahoo.co.in9845087190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026