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Comparison between effect of an analgesic and an antihypertensive on blood pressure and heart rate which are altered due to tracheal intubation.

A comparative study between fentanyl and dexmedetomidine for attenuation of haemodynamic response to laryngoscopy and intubation.

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009857
Enrollment
100
Registered
2017-09-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- AMERICAN SOCIETY OF ANAESTHESIOLOGY STATUS 1 AND 2

Interventions

Intervention1: DEXMEDETOMIDINE: 0.5MICROGRAM/KG BODY WEIGHT DILUTED UPTO 5ML BY ADDING NORMAL SALINE TO BE ADMINISTERED INTRAVENOUSLY. Control Intervention1: FENTANYL: 2MICROGRAM/KG BODY WEIGHT DILUTE

Sponsors

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with ASA physical status 1 and 2. 2.Patients between 18-50 years of age of either sex. 3.Patients with airway of Mallampati grade 1 and 2. 4.Patients willing to participate.

Exclusion criteria

Exclusion criteria: 1.Patient/s refusal to participate. 2.Patients with pregnency, morbid obesity, full stomach and emergency surgery. 3.Patients with ASA physical status 3 and above. 4.Patients with suspected difficult airway and Mallampati grade 3 and 4. 5.Patients in which duration of laryngoscopy is expected to last more than 25 seconds.

Design outcomes

Primary

MeasureTime frame
HEART RATE, MEAN ARTERIAL PRESSURE.Timepoint: 1 MINUTES, 2 MINUTES, 3 MINUTES, 4 MINUTES, 5 MINUTES.

Secondary

MeasureTime frame
OXYGEN SATURATION ADVERSE EFFECTTimepoint: 1 MINUTE, 2 MINUTE, 3 MINUTE, 4 MINUTE, 5 MINUTE

Countries

India

Contacts

Public ContactADITYA PAL MAHISWAR

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES

PKDUBEY@HOTMAIL.COM8962271102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 22, 2026