Health Condition 1: null- Patients with End stage renal disease whoever undergone renal transplantation
Conditions
Interventions
None listed
Sponsors
Dr G Sirisha
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of either gender, aged between 18-70 years and have undergone renal transplantation for end stage renal disease. 2. Patients on stable dose of tacrolimus (2-5 mg), with no change in the dose for at least two weeks. 3. Patients willing to give written informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with co-morbid conditions such as hepatic insufficiency 2. Patients on other drugs which are likely to interact with immunosuppressive drugs. 3. Patients who suffered from gastrointestinal disease, liver disease or other disorders that may alter the absorption of tacrolimus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To determine the genotype of the patients 2.To study trough concentration C0/ dose of tacrolimus in relation to the genotype of the patients Timepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To monitor for graft status 2.To observe incidence of infections and other adverse drug reactions. Timepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr G Sirisha
Nizams Institute of medical sciences
Outcome results
None listed