Health Condition 1: L408- Other psoriasis Health Condition 2: null- palmoplantar psoriasis
Conditions
Interventions
Intervention1: 25 patients will be treated with topical methotrexate solution delivered by iontophoretic device and another 25 patients with clobetasol propionate ointment: evaluate the efficacy of io
Sponsors
Hassan institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1) Palmoplantar psoriasis patients of more than 18 years of age, with lesions preferably on palms but not involving more than 10% surface area of soles and not involving more than 5% of other body surface area. 2) Patients who are not on systemic anti-psoriatic medication for atleast one month or topical anti-psoriatic medication for atleast 15 days prior to the study. 3) Patients who are willing to participate in the study.
Exclusion criteria
Exclusion criteria: 1) Palmoplantar pustular psoriasis patients. 2) Pregnant and lactating women. 3) Female patients of child bearing potential who cannot be convinced of the need of contraception during and 4 months subsequent to the conclusion of study. 4) Patients with cardiac pace makers or orthopedic implants in the extremities. 5) Patients having haematological abnormality, hepatic and renal dysfunction. 6) Patients having any infection of palms and soles.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement in modified Palmo Plantar Pustular Psoriasis Area and Severity Index (m-PPPASI)Timepoint: after 6 weeks of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse effects of treatment and recurrenceTimepoint: follow up for 6 weeks after treatment | — |
Countries
India
Contacts
Public ContactDr Naveen Kumar A C
Hassan institute of medical sciences
Outcome results
None listed