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Effectiveness of ketamine on postoperative pain

Effect of sub-anaesthetic dose of ketamine on postoperative pain relief in patients undergoing modified radical mastectomy(MRM)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009787
Enrollment
75
Registered
2017-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adult women 18-65 years posted for elective modified radical mastectomy under general anaesthesia Health Condition 2: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Placebo: Dose- 5 ml normal saline during induction Frequency- once Route- intravenous Total duration of therapy- bolus administration of drug Control Intervention1: Sub-anaesthetic

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Women within 18-65 years and belonging to ASA 1&2 2. Elective modified radical mastectomy

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Emergency surgery 3. Obesity 4. Patients with coronary artery disease, uncontrolled systemic hypertension, congestive cardiac failure, renal dysfunction/disease, h/o psychiatry and/or seizure disorder 5. On opioid or gabapentinoid medication 6. H/o known allergy to study drug

Design outcomes

Primary

MeasureTime frame
Postoperative painTimepoint: 24 hours postoperative—

Secondary

MeasureTime frame
1. Postoperative nausea and vomiting 2. Intraoperative opioid use 3. Time to extubationTimepoint: Intra and 24 hours postoperative—

Countries

India

Contacts

Public ContactDr Satyajeet Misra

All India Institute of Medical Sciences,Bhubaneswar

misrasatyajeet@gmail.com9438884048

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026