Health Condition 1: null- Borderline Hypertensives
Conditions
Interventions
Intervention1: Dexmeditomidine: 0.5microgm/Kg i.v. Dexmeditomidine10 mins before induction of general anesthesia
Control Intervention1: Labetalol: 0.5 mg/Kg i.v. Labetalol 10 mins before induction o
Sponsors
AIIMS Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 20-60 years 2. Borderline controlled hypertensive (controlled NIBP 3. ASA physical status 4. Planned for laparoscopic cholecystectomy as elective surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Patientsâ??s refusal 2. ASA grade IV 3. Patient taking any antihypertensive medication 4. Patients with ASA physical status of 3 or more 5. Age > 60 years & 6. Cardio-pulmonary compromised patients 7. Major hepatic, Renal or endocrine dysfunction 8. Allergy to anaesthetic drugs used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of dexmedetomidine and labetalol on attenuation of pressure response during laryngoscopy and intubationTimepoint: Pre operative, 5,10 min. post drug administration, after Intubation, before pneumoperitoneum, post pneumoperitoneum at 10,20,30 minutes, release of CO2 and Extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the safety profile in terms of incidence of various side effects such as bradycardia, hypotension, nausea, vomiting.Timepoint: Pre operative, 5,10 min. post drug administration, after Intubation, before pneumoperitoneum, post pneumoperitoneum at 10,20,30 minutes, release of CO2 and Extubation | — |
Countries
India
Contacts
Public ContactDeepak Singla
AIIMS Rishikesh
Outcome results
None listed