Health Condition 1: null- Osteoarthritis Knee
Conditions
Interventions
Intervention1: Dextrose Prolotherapy Group: In group I (Dextrose Prolotherapy Group), patients will receive dextrose prolotherapy in the affected one or both knees. 5ml of 25% Dextrose will be given
Sponsors
Non funded
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 40-65 years, who has 1. Persisting Knee Pain due to OA Knee (Grade II or III, according to radiological classification of knee OA defined by Kellgren and Lawrence) 2. Pain of at-least 40 mm on a 0-100mm VAS when asked â??What is the average level of your Left/ Right knee pain over the last week?â?? 3. Willing to participate in all assessment 4. If both knees involved, participants choose one or both knees to be treated.
Exclusion criteria
Exclusion criteria: 1. Severe OA Knee (Grade IV , according to Kellgren and Lawrence classification) 2. Inflammatory or post-infectious knee arthritis 3. History of prior knee replacement repair 4. Prior knee Prolotherapy 5. Prior fracture of the knee joint 6. Any Knee injection within 3 months 7. Daily use of opioid medication 8. Other chronic pain diagnoses 9. Diabetes mellitus 10. Body mass index (BMI) > 40 kg/m2 11. H/O Anticoagulation therapy 12. Pregnancy 13. Co-morbidity severe enough to prevent participation in the study protocol including at-home exercise or attendance at scheduled injection appointments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario McMaster University Osteoarthritis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score (KOOS) VAS Scale Goniometric ROM of affected Knee Timepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Injection procedure related pain (0, 2 days after injection) Patient SatisfactionTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactApurba Barman
All India Institute of Medical Sciences Bhubaneswar
Outcome results
None listed