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Comparison of application of 2% Turmeric Extract versus 1% Chlorhexidine gel in the treatment of gum diseases

Comparative Evaluation of 2% Turmeric Extract with Nanocarrier and 1% Chlorhexidine Gel as an adjunct to Scaling and Root Planing in Patients with Chronic Periodontitis- A Clinico-Microbiological Study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009730
Enrollment
45
Registered
2017-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with Chronic Periodontitis

Interventions

Intervention1: 2% curcumin gel with nanocarrier: Scaling and Root Planing followed by placement of 2% curcumin gel with nanocarrier as Local Drug Delivery in periodontal pockets Intervention2: 1% chlo

Sponsors

Self Funded
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients clinically diagnosed as localized or Generalized mild to moderate Chronic Periodontitis [According to the AAP 1999 classification] 2. Probing Pocket depth of 5-7mm with two or more teeth 3. No periodontal treatment rendered within the past 6 months

Exclusion criteria

Exclusion criteria: 1. Third molars 2. Patients with endodontic-periodontal lesions 3. Patients using tobacco or tobacco related products 4. Patients with history of antibiotic therapy within past 3 months 5. Patients with known allergy to turmeric and chlorhexidine 6. Patients with any systemic diseases 7. Pregnant women and lactating mothers

Design outcomes

Primary

MeasureTime frame
Plaque Index, Gingival Index, Probing Pocket Depth, Clinical Attachment Level and changes in microbiological parameters.Timepoint: 1st assessment- At baseline (i.e. Day0) 2nd assessment- 21 days post intervention 3rd assessment- 45 days post intervention

Secondary

MeasureTime frame
There are no secondary outcome measuresTimepoint: Not Applicable as we do not have any secondary outcome measures

Countries

India

Contacts

Public ContactDr Adithya Reddy

Vydehi Institute of Dental Sciences and Research Center, Bangalore

sanjeelaguru@yahoo.co.in07259665551

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026