Skip to content

Effect of high oxygen concentration on Surgical site infection in patients undergoing elective colorectal surgery

Effect of perioperative high concentration oxygen supplementation on postoperative surgical site infection in patients undergoing elective colorectal surgery- A randomized controlled trial.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009726
Enrollment
200
Registered
2017-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing elective colorectal surgery under GA

Interventions

Intervention1: High concentration oxygen: Giving High oxygen concentration in perioperative period is beneficial in reducing incidence of surgical site infections Control Intervention1: Surgical site

Sponsors

Jawahar lal Institute of Postgraduate Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients >18 years undergoing elective colorectal surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Minor colorectal procedures including polypectomy where the expected duration of surgery is less than one hour 2.Recent h/o fever, patient with known immunological dysfunction (on steroids, decompensated liver disease, HIV,) 3.Evidence of infection (TLC 12000) 4.Emergency colorectal surgeries done for bowel obstruction 5.Severe malnutrition (albumin 6.Significant co-morbidities- unfit for G A. 7.Respiratory illness- COPD, asthma

Design outcomes

Primary

MeasureTime frame
Surgical site infection postoperatively (according to the CDC criteria up to 30 days)Timepoint: 30 days

Secondary

MeasureTime frame
A.Day of detection of SSI B.Grade of SSI (superficial incisional, deep incisional, organ space) C.Incidence and rate of anastomotic leak and day of detection of leak D.Immediate and early postoperative pain: at 24 hours after surgery and after one week E.Post op analgesic requirement: number of doses, drug/ route F.Return of bowel sound: perception of bowel movements or passage of flatus G.Day of patient ambulation H.Length of hospitalisation: in days Timepoint: 30 days

Countries

India

Contacts

Public ContactVikram Kate

Jawahar lal Institute of Postgraduate Education and Research

drvikramkate@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026