Health Condition 1: null- Spontaneous Intracranial hemorrhage
Conditions
Interventions
Control Intervention1: 1. LMWH SQ Clexane 0.6 ml once daily OD and low dose Aspirin or Ecospirin 150mg OD.
2. Low dose Aspirin or Ecospirin 150mg OD: Patients visiting for consultation with diagnosis
Sponsors
Kasturba medical college Kasturba Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients newly diagnosed with SICH confirmed by coronary tomography (CT) or magnetic resonance imaging (MRI) scans. Patients of both gender, 18 yrs and above. Patients prescribed with either monotherapy (low dose aspirin) or dual therapy (SQ LMWH + Low dose aspirin).
Exclusion criteria
Exclusion criteria: Patients on previous anticoagulant therapy. No available imaging studies, including initial coronary tomography angiography (CTA). Patients previously treated with SICH in another hospital. Patients who are unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Study exposure variables: â?¢ D-dimer values or ultrasound. Primary outcome measures: DVT and pulmonary embolism. Timepoint: Clinical data collection during the hospital stay and follow up at 3 weeks, 3 months and 6 months during the study period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Study exposure variables - Blood pressure (BP) measurement. Coagulation tests including platelet count, PT, APTT, and INR. Study outcome variables â?? CT Scan- Hematoma volume expansion leading to a major SICH. The abrupt onset of focal neurological symptoms such as vomiting, systolic BP 220 mmHg, severe headache, coma or decreased level of consciousness. Prognosis of ICH severity scale estimating an all cause 30-day mortality. Timepoint: Clinical data collection during the hospital stay and follow up at 3 weeks, 3 months and 6 months during the study period. | — |
Countries
India
Contacts
Public ContactSravani Velicheti
Manipal College of Pharmaceutical sciences
Outcome results
None listed