Upper digestive tract bleeding-how much blood to transfuse?

Restrictive vs. Liberal transfusions strategy in patients with upper gastrointestinal bleeding â?? A randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/09/009682

Enrollment

224

Registered

2017-09-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Upper Gastrointestinal bleeding

Interventions

Intervention1: Restrictive transfusion: Transfusing the patient when the hemoglobin is less than 7g/dl till a level of 9g/dl is reached Control Intervention1: Liberal transfusion: Transfusing the pati

Eligibility

Inclusion criteria

Inclusion criteria: All patients >18 years of age presenting with upper GI bleeding with hemoglobin level <10 g/dl

Exclusion criteria

Exclusion criteria: Massive exsanguinating bleeding. Lower GI bleed. An acute coronary syndrome Symptomatic peripheral vasculopathy. Stroke, transient ischemic attack. Transfusion within 90 days. A recent history of trauma or surgery.

Design outcomes

Primary

Measure	Time frame
MORTALITY MORBIDITYTimepoint: 45 DAYS	—

Secondary

Measure	Time frame
Banding or sclerotherapyTimepoint: 45 days;Death from any cause within 45 daysTimepoint: 45 days;Dose and duration of octreotideTimepoint: 45 days;Length of hospital stayTimepoint: 45 days;Number of sessions of endoscopic treatmentTimepoint: 45 days;Rebleeding episodesTimepoint: 45 days;Requirement of Sengstaken Blakemore tube placementTimepoint: 45 days	—

Countries

India

Contacts

Public ContactDr Sreenath GS

Jawaharlal Institute of Post Graduae Medical Education and Research

dr.sreenathgs@gmail.com9486690883

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026