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Vitamin D supplementation in infertile males with decreased sperm count and motility.

IMPACT OF VITAMIN D SUPPLEMENTATION ON SEMEN QUALITY IN VITAMIN D DEFICIENT INFERTILE MALES WITH OLIGOASTHENOZOOSPERMIA

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009678
Enrollment
30
Registered
2017-09-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Infertility

Interventions

Intervention1: Vitamin D supplementation: 60,000 IU cholecalciferol once weekly for 3 months. Control Intervention1: NIL: NIL

Sponsors

ESI PGIMSR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Infertile males meeting the WHO criteria for oligospermia or asthenozoospermia, i.e. sperm concentration 2) Males asymptomatic for vitamin D deficiency.

Exclusion criteria

Exclusion criteria: 1) Men with history of any chronic illness, endocrine or metabolic disorders or malignancy. 2) History of intake of vitamin D for preceding 3 months. 3) History of testicular infection, testicular mumps, cryptorchidism, varicocelectomy, testicular biopsy. 4) Males with vitamin D level > 30 ng/ml 5) Males with azoospermia.

Design outcomes

Primary

MeasureTime frame
1) Semen parameters- sperm concentration, sperm motilityTimepoint: 3 months—

Secondary

MeasureTime frame
) Levels of reproductive hormone profile- FSH, LH, Testosterone, Estradiol. 2) Levels of bone regulating hormones- Alkaline phosphatase, serum calcium, serum phosphate. 3) Effect on pregnancy outcomes Timepoint: 6 months—

Countries

India

Contacts

Public ContactDr Srishti Priyadarshini

Employee State Insurance-Post Graduate Institute of Medical Science and Research

doc.srishti187@gmail.com8826813316

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026