Health Condition 1: null- oral submucous fibrosis
Conditions
Interventions
Intervention1: Group A Tablet Curcumin and Piperine 300 mg: 300 mg tablet was administered orally twice daily for 6 months
Intervention2: Group B Tablet Lycopene 16 mg: 16 mg tablet was administered o
Sponsors
Maulana Azad Institute of Dental Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Clinically & Histopatholically proven cases of OSMF a positive history of chewing areca nut, tobacco, betel quid, smoking and alcohol difficulty in swallowing, chewing and burning sensation on eating spicy foods restricted mouth opening and changes in the oral mucous membrane including the presence of palpable vertical fibrous bands, stiffness and blanching.
Exclusion criteria
Exclusion criteria: those who are not willing to participate patients who are already undertaking some treatment for existing potentially malignant oral disorder patients with severe systemic disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| evaluation of burning sensation score, mouth opening, tongue protrusion and cheek flexibility between groups and within groupTimepoint: patients were assessed clinically every 4 weeks for 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Reporting of malignant transformation over period of 9 monthsTimepoint: patients were assessed clinically every 4 weeks for 9 months. in case of any suspicion biopsy was done | — |
Countries
India
Contacts
Public ContactDr Anshul Mahajan
Maulana Azad Institute of Dental Sciences
Outcome results
None listed