Comparison of Aloevera gel and Curcumin gel in Oral submucous fibrosis.

A randomised open label parallel study to compare the safety and efficacy of Aloevera gel and Curcumin gel as add on therapy in patients of Oral submucous fibrosis

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/09/009666

Enrollment

105

Registered

2017-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K135- Oral submucous fibrosis Health Condition 2: null- Patients of Oral Submucous Fibrosis

Interventions

Intervention1: Aloe Vera Gel with intralesional Triamcinolone 40 mg: Topical Application,thrice a day for 12 weeks Intervention2: Curcumin gel with intralesional Triamcinolone 40 mg: Topical Applicati

Eligibility

Inclusion criteria

Inclusion criteria: Newly diagnosed patients of Oral submucous fibrosis. Old patients of submucous fibrosis who have left treatment 6 weeks before.

Exclusion criteria

Exclusion criteria: Patients with chronic diseases like TB, DM, AIDS. Any other Oral mucosal lesions along with Oral submucous fibrosis. Pregnant patients and lactating mothers.

Design outcomes

Primary

Measure	Time frame
1:Improvement in Burning sensation 2:Interincisal distance 3: Tongue protusionTimepoint: All the three parameters will be evaluated at the end of 4, 8,12 week.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDarakhshan Rizvi

Eras lucknow medical college & hospital

aliahmad786110@gmail.com9559695171

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026