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A clinical study comparing early feeding with late feeding initiation in premature newborn babies with abnormal ultrasound Doppler blood flow in the umbilical arteries.

A Study on enteral feeding of Low birth weight babies with abnormal antenatal Doppler flow patterns: A Randomized open label controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009641
Enrollment
62
Registered
2017-09-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Preterm intrauterine growth restricted neonates below 33 weeks period of gestation with absent or reversed end diastolic flow on umbilical artery Doppler flow studies done antenatally

Interventions

Intervention1: Early feeding: Early feeding was defined as initiation of expressed breast milk (EBM) feeding within 12 to 48 hours after birth Control Intervention1: Late feeding: Late feeding was def

Sponsors

Vishal Vishnu Tewari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Intramural preterm IUGR neonates below 33 weeks with AREDF on UA Doppler and admitted to the NICU

Exclusion criteria

Exclusion criteria: Neonates, who were extramural, symmetric IUGR, or had antenatally suspected intestinal anomaly, lethal congenital anomaly, clinical suspicion of genetic aberration, needed invasive ventilation, inotropic support or extensive resuscitation and unavailable parent were excluded. Intramural preterm IUGR neonates < 27 weeks were also excluded.

Design outcomes

Primary

MeasureTime frame
Incidence of necrotizing enterocolitis (NEC) in neonates fed early versus late.Timepoint: From admission to discharge from the neonatal intensive acre unit (NICU)

Secondary

MeasureTime frame
Secondary outcomes were incidence of FI, time to achieve adequate enteral intake allowing discontinuation of PN, time to attainment of full feeds, time to regain birth weight, incidence of LOS, duration of hospital stay and all-cause mortality.Timepoint: From admission to discharge from the neonatal intensive care unit (NICU)

Countries

India

Contacts

Public ContactVishal Vishnu Tewari

Army Hospital (Referral and Research) New Delhi

docvvt_13@hotmail.com8826118889

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026