a clinical trial between two surgical solutions povidone iodine and chlorhexidine for surgical dressing before vaginal route of hysterectomy

A randomised trial of povidone iodine and chlorhexidine as solutions for surgical preparation of vaginal hysterectomy

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/09/009630

Enrollment

Registered

2017-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Those who have pelvic organ prolpase and are planned for vaginal hysterectomy

Interventions

Intervention1: Povidone Iodine: Povidone Iodine 10% will be used for surgical dressing before vaginal hysterectomy Control Intervention1: Chlorhexidine 4% solution: Chlorhexidine 4% will be used for s

Eligibility

Inclusion criteria

Inclusion criteria: Patients planned and posted for vaginal hysterectomy, after admission will be offered enrolment after taking informed consent from patient.

Exclusion criteria

Exclusion criteria: Patient-reported allergy to iodine. Any local infection Patients on immunosuppressive therapy e.g. corticosteroids, HIV infected patients

Design outcomes

Primary

Measure	Time frame
1. To compare the efficacy of chlorhexidine and povidone iodine solutions for cleansing the operative field for vaginal hysterectomy. 2. To assess post- operative infectious morbidity within 4 weeks of vaginal hysterectomy. 3. To note serious adverse events associated with use of either type of antiseptics. Timepoint: during the procedure	—

Secondary

Measure	Time frame
Febrile morbidity Bleeding Urinary infection Wound infection Wound breakdown Timepoint: NIL	—

Countries

India

Contacts

Public ContactDr Monika Anant

AIIMS Patna

drmonika.anant@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026