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to study the risk factors and incidence of raised intraocualar pressure following corneal transplantation and see the management protocol

Study of post keratoplasty glaucoma and comparative evaluation of fixed combination versus dual therapy in management of raised intraocular pressure

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/09/009604
Enrollment
30
Registered
2017-09-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- post keratoplasty glaucoma

Interventions

Intervention1: Eyedrop Timolol 0.5% and Eyedrop Brimonidine 0.2%: Comparison of effect on iop with fixed combination of Timolol and Brimonidine two times/day 1 drop versus individual component therapy

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Intraocular pressure >21 mm Hg 2 Patients who are willing to participate

Exclusion criteria

Exclusion criteria: 1 Pregnant and lactating mothers 2 Non compliance with study procedures 3 Pre existing glaucoma

Design outcomes

Primary

MeasureTime frame
to compare topical fixed combination versus separate dual therapy in managing IOP in patients with post keratoplasty glaucoma(timolol 0.5% + brimonidine 0.2%)Timepoint: IOP less than 21 mm Hg will be assessed at 1 week, 1 month, 3 month, 6 month, 9 month and 1 year—

Secondary

MeasureTime frame
to study pattern and risk factors for post keratoplasty glaucoma estimate incidence and determine clinical spectrumTimepoint: incidence of post keratoplasty glaucoma and risk factors associated for it will be assesed at the end of 9 months and 1 year—

Countries

India

Contacts

Public ContactAlisha Kishore

All India Institute of Medical Sciences, Delhi

radhika_tan@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026