A study to develop and test the effects of Meaningful Coma arousal technique after Accidental Brain Injury

Developing and Testing of Meaningful Multimodal Sensory Stimulation in patients with Coma following Traumatic Brain Injury

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/09/009599

Enrollment

Registered

2017-09-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere Health Condition 2: null- Traumatic Brain Injury

Interventions

Intervention1: Meaningful Multimodal Sensory stimulation: Various Meaningful Stimuli (auditory,tactile,gustatory,vestibular,proprioceptive,visual)will be given in a functional position to patients an

Eligibility

Inclusion criteria

Inclusion criteria: Who are haemodynamically stable and shifted out of ICU, have a GCS score less than 8, and minimum of 48 hours after surgery or conservative management.

Exclusion criteria

Exclusion criteria: Who have a previous history of Brain Damage,known case of impaired vision and hearing,active Otorrhoea or Rhinorrhea (signs of CSF leak),Coma or persistent vegetative state not caused by TBI,patients with autonomic dysfunction and unstable Long bone fracture, associated injuries

Design outcomes

Primary

Measure	Time frame
Coma recovery scale revised (CRS-R)Timepoint: 1 st day, end of 1st week and end of 2nd week	—

Secondary

Measure	Time frame
Sensory stimulation Assessment Measure (SSAM)Timepoint: 1 st day, end of 1st week and end of 2nd week	—

Countries

India

Contacts

Public ContactDrN Manikandan

School of Allied Health Sciences

john.solomon@manipal.edu9945670671

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026