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To study different systemic drugs for pain of herpes zoster

To study the safety and efficacy of different systemic treatment modalities with antiviral drug for acute pain and chronic pain of herpes zoster- A Pilot study - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/08/009585
Enrollment
45
Registered
2017-08-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Acute pain in Herpes Zoster

Interventions

Intervention1: Valacyclovir (1gm Tds x 7days) with pregabalin(75mg bd x 1 month) and Valacyclovir(1gm Tds x 7days),Pregabalin pregabalin(75mg bd x 1 month) with Methyprednisolone (16mg bd x 7 days):

Sponsors

Dr sanjiv choudhary
Lead Sponsor
No sponsor
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) All patients of Herpes zoster of eruptions less than 72 hours duration. 2) Patients with age group 18 years to 70 years of both genders. 3) Patients willing to participate 3) Herpes zoster ophthalmicus without corneal involvement.

Exclusion criteria

Exclusion criteria: 1) Herpes zoster in pregnant and lactating patients. 2) Age less than 18 years and more than 70 years. 3) Herpes zoster ophthalmicus with keratitis. 4) Herpes zoster patients with diabetes mellitus, hypertension, tuberculosis, gastro-intestinal ulcer disease or with immune-compromised condition 5) Cases of disseminated Herpes zoster infection. 6) Patients of cardiac arrhythmia and cardiac disease 7) Patient with known hypersensitivity for drugs over study.

Design outcomes

Primary

MeasureTime frame
Improvement in the severity of pain both in percentage (100-76%: excellent, 75-51%: good, 50-26%: moderate, 25% and less: poor) and grade (mild-pain perceived but day activities and night sleep not affected, moderate- day activities not affected but night sleep affected, severe-both day activities and night sleep affected) was noted. Timepoint: measured at end of 1, 4, 6 weeks

Secondary

MeasureTime frame
Patients were monitored for side-effects during follow up period.Timepoint: monitored at end of 1, 4, 6 weeks

Countries

India

Contacts

Public ContactDr Sanjiv Choudhary

DMIMS

sanjiv_choudhary26@yahoo.com9823165012

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026