Health Condition 1: null- Dengue
Conditions
Interventions
Intervention1: Caripill: Carica Papaya Leaf Extract tablets
1100mg t.i.d for 5 days
Control Intervention1: Placebo: 1100mg t.i.d for 5 days
Sponsors
Micro Labs Limited
Eligibility
Inclusion criteria
Inclusion criteria: 1. Provide signed and dated informed consent form 2. Willing to comply with all study procedures and be available for the duration of the study 3. Male or female, aged greater than or equal to 18 yrs of age. Clinically diagnosed of dengue and a peripheral platelet count of less than or equal to 30,000/µL. 4. A laboratory positive diagnosis of dengue confirmed by a positive NS1 ELISA test and/or detection of viral RNA by real time PCR assay.
Exclusion criteria
Exclusion criteria: 1. Pregnancy and lactation. 2. Patients who has been given steroids for thrombocytopenia and also those who have been transfused platelets before starting the drug 3. Taking indigenous medicines. 4. Creatine kinase (CK) >1000 U/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of peak platelet counts and hematocrit levels between the treatment and placebo groups. Comparison of the frequency and type of blood product, more specifically platelet transfusions between the treatment and placebo groups. Timepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of platelet counts with phases of dengue Compare and evaluate the correlation of viremia with peripheral platelet counts between the treatment and placebo groupsTimepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Vidya P Menon
Amrita Institute of Medical Sciences
Outcome results
None listed