Health Condition 1: null- Alcohol Dependence
Conditions
Interventions
Intervention1: Right sided intermittent theta burst and left sided continuous theta burst stimulation type of repetitive transcranial magnetic stimulation: Right sided intermittent theta burst and lef
Sponsors
Dr Vivek Benegal
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients meeting ICD-10 criteria for alcohol dependence as determined by two independent clinicians at the Centre for Addiction Medicine, NIMHANS 2.Either gender 3.Right handed 4.Age between 18 and 50 years 5.CIWA Ar score of 0 at treatment initiation
Exclusion criteria
Exclusion criteria: 1.Presence of past complicated withdrawal 2.Presence of significant medical or neurological illnesses 3.Presence of intellectual impairments or clinically significant cognitive deficits known to be associated with alcohol use disorders 4.Presence of any of the risk factors for TMS procedures as assessed using â??Screening standard questionnaire for rTMS candidatesâ??
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Change in craving scale scores Changes in pre-frontal neurohemodynamics as measured by fNIRS during performance of a stop signal task and a cue induced craving task; Visual Image Induced Craving for Ethanol (VICE) protocol Time to lapseTimepoint: Baseline, 1 week Baseline, 1 week Upto 3 months | — |
Primary
| Measure | Time frame |
|---|---|
| Change in impulsivity as measured by response inhibition using the performance on Stop Signal TaskTimepoint: Baseline, 1 week | — |
Countries
India
Contacts
Public ContactJayant Mahadevan
National Institute of Mental Health and Neurosciences
Outcome results
None listed