Health Condition 1: null- All intramural preterm neonates admitted to NICU with proven sepsis
Conditions
Interventions
Intervention1: Zinc: Zinc group was given
oral zinc 10 mg once a day irrespective of age of newborn till discharge.
Intervention2: Pre-Probiotics: Pre-Probiotics group was given as Syrup 5ml per day
Sponsors
Govt Medical College Aurangabad
Eligibility
Inclusion criteria
Inclusion criteria: All intramural preterm neonates from 28wk1day to 36wk6days admitted to NICU at GMCH Aurangabad with proven sepsis during the study period, whose parents consented to be part of the study were included. Diagnostic criteria for sepsis was (a) Positive â??sepsis screenâ?? i.e. presence of at least two of the following three parameters, namely, Total leucocyte count 1mg/dl, (b) Radiological evidence of pneumonia (c) Culture positive sepsis (d) Meningitis
Exclusion criteria
Exclusion criteria: Parental refusal to consent, neonates severe birth asphyxia, life threatening congenital malformations, critically ill newborns within 24 hours of life, neonates with necrotizing enterocolitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in MortalityTimepoint: at discharge/30 days of life | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospital stayTimepoint: At discharge/ 30 days of life;Need for change to higher (2nd/3rd line) antibioticsTimepoint: At discharge/ 30 days of life;Need for supportive treatment i.e ventilation, inotropes, blood transfusionTimepoint: At discharge/ 30 days of life | — |
Countries
India
Contacts
Public ContactDr Atul Londhe
Govt Medical College, Aurangabad
Outcome results
None listed